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Anti-Pro-Decorin polyclonal antibody

Cat no: CABT-B1824

Anti-Pro-Decorin polyclonal antibody

Rabbit Anti-Human Pro-Decorin polyclonal antibody for IHC. Decorin (UniProt P07585; also known as Bone proteoglycan II, PG40, PG-S2) is encoded by the DCN (also known as DSCD, DSPG2, PGII, PGS2, SLRR1B) gene (Entrez Gene ID 1634) in human. Decorin is a pericellular matrix proteoglycan structurally related to two other small proteoglycans, biglycan and fibromodulin. Decorin and biglycan are thought to be the result of a gene duplication. Decorin contains one attached glycosaminoglycan chain, while biglycan contains two chains. Decorin modulates collagen fibril formation as well as the bioactivity of various members of the transforming growth factor-beta (TGFbeta) superfamily. Decorin is initially translated as a preproprotein with an N-terminal signal peptide (aa1-16) and propeptide (aa17-30) sequence. Sequential removal of the signal peptide and the propeptide sequence produces pro- and mature decorin, respectively.

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SPECIFICATIONS

Catalog Number

CABT-B1824

Hosts

Rabbit

Reactivities

Hum, Mouse

Target

DCN

Gene Id

1634

Clonality

Polyclonal

Storage Temp

Stable for 1 year at -20В°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20В°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.

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