Anti-RLIM polyclonal antibody

Cat no: CABT-B1930

Supplier: Creative Diagnostics

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Rabbit Anti-Mouse RLIM polyclonal antibody for WB, IF, IHC, ChIP, ICC. E3 ubiquitin-protein ligase RLIM (UniProt Q9WTV7; also known as Hoxa1 regulated, LIM domain-interacting RING finger protein, R-LIM, RING finger LIM domain-binding protein, Ring finger protein 12) is encoded by the Rlim (also known as AL022832, AW743871, Ha1r, Rlim1, Rnf12) gene (Gene ID 19820) in murine species. The CLIM/LDB/NLI and RLIM/RNF12 cofactors are transcriptional coregulatory proteins characterized by their ability to bind the LIM domains of nuclear LIM proteins, including LIM homeodomain (LIM-HD) transcription factors. The association of CLIM with LIM-HDs positively regulate their biological and transcriptional activity. On the other hand, the RING finger ubiquitin ligase RLIM acts as a negative regulator of LIM-HD activity by interacting with and targeting CLIM for degradation via the ubiquitin-proteasome pathway.

Catalogue number:	CABT-B1930
Reactivities:	Human, Mouse, Hamster
Hosts:	Rabbit
Applications:	ChIP
Target:	RLIM
Clonality:	Polyclonal
Storage temp:	Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.

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Anti-RLIM polyclonal antibody

Cat no: CABT-B1930

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