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Anti-RNASEH2A (internal region) polyclonal antibody

Anti-RNASEH2A (internal region) polyclonal antibody

Cat no: CABT-BL3160

Supplier: Creative Diagnostics
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Rabbit Anti-Human RNASEH2A polyclonal antibody for WB, ELISA, ICC. The protein encoded by this gene is a component of the heterotrimeric type II ribonuclease H enzyme (RNAseH2). RNAseH2 is the major source of ribonuclease H activity in mammalian cells and endonucleolytically cleaves ribonucleotides. It is predicted to remove Okazaki fragment RNA primers during lagging strand DNA synthesis and to excise single ribonucleotides from DNA-DNA duplexes. Mutations in this gene cause Aicardi-Goutieres Syndrome (AGS), a an autosomal recessive neurological disorder characterized by progressive microcephaly and psychomotor retardation, intracranial calcifications, elevated levels of interferon-alpha and white blood cells in the cerebrospinal fluid.[provided by RefSeq, Aug 2009]
Catalogue number: CABT-BL3160
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Applications: ELISA
Conjugates: Unconjugated
Gene: 10535
Target: RNASEH2A
Isotype: IgG
Clonality: Polyclonal
Storage temp: Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze / thaw cycles.

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