Anti-S100B polyclonal antibody [Cy7]

Rabbit Anti-S100B polyclonal antibody. S100 beta is a member of the S100 family of proteins containing 2 EF-hand calcium binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21; however, this gene is located at 21q22.3. This protein may function in neurite extension, proliferation of melanoma cells, stimulation of Ca2+ fluxes, inhibition of PKC mediated phosphorylation, astrocytosis and axonal proliferation, and inhibition of microtubule assembly. Chromosomal rearrangements and altered expression of this gene have been implicated in several neurological, neoplastic, and other types of diseases, including Alzheimer's disease, Down's syndrome, epilepsy, amyotrophic lateral sclerosis, melanoma, and type I diabetes.

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SPECIFICATIONS

Catalog Number

CABT-B8707

Hosts

Rabbit

Reactivities

Hum, Mouse, Rat, Rabbit

Target

S100B

Isotype

IgG

Clonality

Polyclonal

Storage Temp

Store at -20В°C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20В°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of anti