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Anti-SART3 (aa 951-963) polyclonal antibody

Cat no: CABT-BL3234

Anti-SART3 (aa 951-963) polyclonal antibody

Goat Anti-Human SART3 polyclonal antibody for ELISA, WB. This gene encodes two proteins, the SART1(800) protein expressed in the nucleus of the majority of proliferating cells, and the SART1(259) protein expressed in the cytosol of epithelial cancers. The SART1(259) protein is translated by the mechanism of -1 frameshifting during posttranscriptional regulation; its full-length sequence is not published yet. The two encoded proteins are thought to be involved in the regulation of proliferation. Both proteins have tumor-rejection antigens. The SART1(259) protein possesses tumor epitopes capable of inducing HLA-A2402-restricted cytotoxic T lymphocytes in cancer patients. This SART1(259) antigen may be useful in specific immunotherapy for cancer patients and may serve as a paradigmatic tool for the diagnosis and treatment of patients with atopy. The SART1(259) protein is found to be essential for the recruitment of the tri-snRNP to the pre-spliceosome in the spliceosome assembly pathway. [provided by RefSeq, Jul 2008]

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SPECIFICATIONS

Catalog Number

CABT-BL3234

Applications

ELISA

Hosts

Goat

Reactivities

Hum

Conjugates

Unconj

Target

SART

Gene Id

9733

Isotype

IgG

Clonality

Polyclonal

Storage Temp

Shipped at 4В°C. Upon delivery aliquot and store at -20В°C or -80В°C. Avoid repeated freeze / thaw cycles.

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