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Anti-SCD1 polyclonal antibody

Cat no: CABT-B1818

Anti-SCD1 polyclonal antibody

Rabbit Anti-Mouse SCD1 polyclonal antibody for WB, IHC. Fatty acid desaturases (FADS) catalyze the formation of carbon/carbon double bonds in fatty acids. Stearoyl-CoA desaturase 1 (Scd1), in particular, is an FADS that catalyzes the synthesis of oleic acid by introducing a double bond between C9 and C10 from the carboxyl end of stearic acid. Scd1 activity is essential for the earliest step of autophagosome formation, whose membrane has a high content of unsaturated fatty acids. Scd1 is reported to regulate inflammatory gene expression in adipocytes by influencing DNA methylation at the CpG promoter sites, Scd1 overexpression or silencing results in global DNA hypomethylation or hypermethylation, respectively, in 3T3 adipocytes. Stearoyl-CoA desaturase 1 is a novel therapeutic target in various malignancies, including breast cancer.

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SPECIFICATIONS

Catalog Number

CABT-B1818

Hosts

Rabbit

Reactivities

Mouse, Rat

Target

SCD1

Clonality

Polyclonal

Storage Temp

Stable for 1 year at -80В°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -80В°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.

SUPPLIER INFO

Creative Diagnostics

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