Anti-SEPT11 polyclonal antibody

Cat no: CABT-B1947

Supplier: Creative Diagnostics

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Rabbit Anti-Rat SEPT11 polyclonal antibody for WB, IHC. Septin-11 is encoded by the Sept11 gene in rat and mouse (SEPT11 in human). Septins are GTP-binding proteins capable of forming higher-order oligomers and filamentous polymers that contact with the cell membrane and cytoskeleton. Septins are involved in various cellular processes, including cytokinesis, karyokinesis, exocytosis, and cell shape maintenance. Evidence indicates that septin-11 plays important roles in the cytoarchitecture of rat brain neurons, including dendritic arborization and dendritic spines, as well as in GABAergic synaptic connectivity. Septin-11 is also reported to be involved in host defense against Listeria surface protein InlB-mediated invasion in non-phagocytic cells in human. In addition, Septin-11 is identified to be enriched in the detergent-insoluble protein extracts prepared from frontal cortex of FTLD-U (frontotemporal lobar degeneration with ubiquitin-immunoreactive inclusions) patients.

Catalogue number:	CABT-B1947
Reactivities:	Rat
Hosts:	Rabbit
Target:	SEPT11
Clonality:	Polyclonal
Storage temp:	Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.

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Anti-SEPT11 polyclonal antibody

Cat no: CABT-B1947

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