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Anti-SF3B1 (aa 1-50) polyclonal antibody

Cat no: CABT-BL5619


Supplier: Creative Diagnostics
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Rabbit Anti-Human SF3B1 (aa 1-50) polyclonal antibody for WB, IHC-P, ICC/IF. This gene encodes subunit 1 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the introns branch site in a sequence independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. The carboxy-terminal two-thirds of subunit 1 have 22 non-identical, tandem HEAT repeats that form rod-like, helical structures. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Catalogue number: CABT-BL5619
Reactivities: Human
Hosts: Rabbit
Conjugates: Unconjugated
Gene: 23451
Target: SF3B1
Isotype: IgG
Clonality: Polyclonal
Storage temp: Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze/thaw cycles.

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