Anti-SIRPA monoclonal antibody, clone 110

Rabbit Anti-SIRPA monoclonal antibody for ELISA. The protein encoded by this gene is a member of the signal-regulatory-protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. This protein can be phosphorylated by tyrosine kinases. The phospho-tyrosine residues of this PTP have been shown to recruit SH2 domain containing tyrosine phosphatases (PTP), and serve as substrates of PTPs. This protein was found to participate in signal transduction mediated by various growth factor receptors. CD47 has been demonstrated to be a ligand for this receptor protein. This gene and its product share very high similarity with several other members of the SIRP family. These related genes are located in close proximity to each other on chromosome 20p13. Multiple alternatively spliced transcript variants have been determined for this gene.

Prices direct from Creative Diagnostics

Quick response times

Exclusive Biosave savings/discounts

SPECIFICATIONS

Catalog Number

CABT-B8967

Applications

ELISA

Hosts

Rabbit

Reactivities

Mouse

Clone

110

Target

SIRPA

Gene Id

19261

Isotype

IgG

Clonality

monoclonal

Storage Temp

This antibody can be stored at 2В°C-8В°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20В°C to -80В°C. Preservative-Free.<br/>Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.