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Anti-SMAD1+5+8(9) (C-terminal) polyclonal antibody, clone D2D4-4

Cat no: CABT-B971

Anti-SMAD1+5+8(9) (C-terminal) polyclonal antibody, clone D2D4-4

Rabbit Anti-Human SMAD1+5+8(9) polyclonal antibody for WB. The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene mothers against decapentaplegic (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signals of the bone morphogenetic proteins (BMPs), which are involved in a range of biological activities including cell growth, apoptosis, morphogenesis, development and immune responses. In response to BMP ligands, this protein can be phosphorylated and activated by the BMP receptor kinase. The phosphorylated form of this protein forms a complex with SMAD4, which is important for its function in the transcription regulation. This protein is a target for SMAD-specific E3 ubiquitin ligases, such as SMURF1 and SMURF2, and undergoes ubiquitination and proteasome-mediated degradation. Alternatively spliced transcript variants encoding the same protein have been observed.

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SPECIFICATIONS

Catalog Number

CABT-B971

Hosts

Rabbit

Reactivities

Hum, Mouse, Rat, Bov

Conjugates

Unconj

Clone

D2D4-4

Target

SMAD1

Isotype

IgG

Clonality

polyclonal

Storage Temp

Keep as concentrated solution. Aliquot and store at -20В°C or below. Avoid multiple freeze-thaw cycles.

SUPPLIER INFO

Creative Diagnostics

Applications

ELISA

Hosts

Rabbit

Reactivities

Hum

Conjugates

Unconj

More info

Hosts

Mouse

Reactivities

Hum

Conjugates

Unconj

More info

Hosts

Rabbit

Reactivities

Hum

Conjugates

Unconj

More info

Hosts

Mouse

Reactivities

Hum

Conjugates

Unconj

More info

Hosts

Rabbit

Reactivities

Hum

Conjugates

Unconj

More info

Hosts

Rabbit

Reactivities

Hum

Conjugates

Unconj

More info

Hosts

Rabbit

Reactivities

Hum

Conjugates

Unconj

More info

Hosts

Rabbit

Reactivities

Hum

Conjugates

Unconj

More info

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