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Anti-SPTLC3 polyclonal antibody

Anti-SPTLC3 polyclonal antibody

Cat no: CABT-BL4051

Supplier: Creative Diagnostics
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Rabbit Anti-Human SPTLC3 polyclonal antibody for WB, IHC. The SPTLC3 gene encodes an isoform of the third subunit of serine palmitoyltransferase (SPT; EC 2.3.1.50), which catalyzes the rate-limiting step of the de novo synthesis of sphingolipids (Hornemann et al., 2006 [PubMed 17023427]). SPT contains 2 main subunits: the common SPTLC1 subunit (MIM 605712) and either SPTLC2 (MIM 605713) or its isoform SPTLC2L (SPTLC3), depending on the tissue in which biosynthesis occurs (Hornemann et al., 2006 [PubMed 17023427]). There are also 2 highly related isoforms of a third subunit, SSSPTA (MIM 613540) and SSSPTB (MIM 610412), that confer acyl-CoA preference of the SPT enzyme and are essential for maximal enzyme activity.
Catalogue number: CABT-BL4051
Reactivities: Human
Hosts: Rabbit
Gene: 55304
Target: SPTLC3
Isotype: IgG
Clonality: polyclonal
Storage temp: Store at +4°C for short term storage. Long time storage is recommended at -20°C.

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