Mouse anti-Superoxide Dismutase Cu/Zn monoclonal antibody for ELISA, WB. Suitable for use in ELISA and Western blot (reducing conditions). Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.Defects in SOD1 arethe cause of amyotrophic lateral sclerosis type 1 (ALS1) [MIM:105400]. ALS1is a familial form of amyotrophic lateral sclerosis, a neurodegenerativedisorder affecting upper and lower motor neurons and resulting in fatalparalysis. Sensory abnormalities are absent. Death usually occurs within 2 to5 years. The etiology of amyotrophic lateral sclerosis is likely to bemultifactorial, involving both genetic and environmental factors. The diseaseis inherited in 5-10% of cases leading to familial forms.
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