Mouse Anti-T. gondii Monoclonal antibody for ELISA, IB, IF. Toxoplasmais a crescent shaped sporozoan that lives as an intracellular parasite invarious tissues of many vertebrates and completes its life cycle in a singlehost. Its life cycle includes two phases called the intestinal (orenteroepithelial) and extraintestinal phases. The intestinal phase producesoocysts and occurs only in cats, wild as well as domesticated. Theextraintestinal phase occurs in all infected animals including cats, andproduces tachyzoites (actively proliferating trophozoites) and eventually,bradyzoites (slowly growing trophozoites) or zoitocysts. Infection due toToxoplasma gondii occurs in pregnant women where a variable degree ofimmunosuppression may exist or in patients receiving immunosuppressive drugtherapy. Toxoplasma infects tissue of the GI tract where an active infectionis accompanied by fever and enlargement of the spleen. Symptoms oftoxoplasmosis are generally mild but severe infection of lymph nodes mayoccur. Congenital toxoplasmosis, in which the maternal infection istransmitted during pregnancy, can produce blindness or mental retardation inthe newborn.
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