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Anti-TBP/TATA Binding Protein Monoclonal Antibody (2C6)

Cat no: A01120

Anti-TBP/TATA Binding Protein Monoclonal Antibody (2C6)

General transcription factor that functions at the core of the DNA-binding multiprotein factor TFIID. Binding of TFIID to the TATA box is the initial transcriptional step of the pre-initiation complex (PIC), playing a role in the activation of eukaryotic genes transcribed by RNA polymerase II. Component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC (preinitiation complex) during RNA polymerase I-dependent transcription. The rate of PIC formation probably is primarily dependent on the rate of association of SL1 with the rDNA promoter. SL1 is involved in stabilization of nucleolar transcription factor 1/UBTF on rDNA.

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SPECIFICATIONS

Catalog Number

A01120

Size

50micro l, 200micro l, 1ml, 10ml

Applications

WB

Hosts

Mouse

Reactivities

Hum, Mouse, Rat

Gene Id

6908

Isotype

Mouse IgG

Accession

P20226

Clonality

Monoclonal

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