Anti-Testosterone monoclonal antibody, clone A7004

Mouse Anti-Testosterone monoclonal antibody for ELISA. Suitable for use in ELISA. Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excludedTestosterone is asteroid hormone from the androgen group and is found in mammals, reptiles,birds, and other vertebrates. In mammals, testosterone is primarily secretedin the testes of males and the ovaries of females, although small amounts arealso secreted by the adrenal glands. It is the principal male sex hormone andan anabolic steroid.In men, testosterone plays a key role in the developmentof male reproductive tissues such as the testis and prostate as well aspromoting secondary sexual characteristics such as increased muscle, bonemass and the growth of body-hair. In addition, testosterone is essential forhealth and well-being as well as the prevention of osteoporosis.On average, an adult human male body produces about ten times moretestosterone than an adult human female body, but females are more sensitiveto the hormone. Testosterone is conserved through most vertebrates, althoughfish make a slightly different form called 11-ketotestosterone. Itscounterpart in insects is ecdysone. These ubiquitous steroids suggest thatsex hormones have an ancient evolutionary history.Testosterone is the principal androgen, or male sex hormone. One of the groupof compounds known as anabolic steroids, testosterone is secreted by thetestes but is also synthesized in small quantities in the ovaries, corticesof the adrenal glands, and placenta, usually from cholesterol. Testosteroneis necessary in the fetus for the development of male external genitalia.Testosterone also stimulates protein synthesis and accounts for the greatermuscular development of the male. For many years, synthetic steroids similarto testosterone have been used by athletes with the goal of improvingperformance, although recent medical research has shown that these drugs mayhave a wide range of harmful side effects.

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