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anti-TIMP Metallopeptidase Inhibitor 4 (TIMP4) antibody

Cat no: ABIN1043744

anti-TIMP Metallopeptidase Inhibitor 4 (TIMP4) antibody

anti-TIMP Metallopeptidase Inhibitor 4 (TIMP4) antibody: Tissue inhibitor of metalloproteinase-4 (TIMP-4) is member of the TIMP family of inhibitors of matrix metalloproteinase (MMP) activities. In addition, TIMPs have non-MMP associated functions, including roles in growth promotion, apoptosis, and angiogenesis. All four members of the TIMP gene family form a similar secondary structure due to the formation of six highly conserved disulfide bonds. It has been reported that some TIMPs, TIMP4 included, can bind a tetraspanin in the plasma membrane, initiating an intra-cellular signaling cascade. Elevated levels of TIMP4 have been associated with breast cancer progression and heart disease.

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SPECIFICATIONS

Catalog Number

ABIN1043744

Size

25 micro L

Applications

ELISA, IHC, WB

Hosts

Mouse

Reactivities

Hum, Mouse

Clone

9:4-7

Antigen

TIMP4

Gene Id

7079,110595

Isotype

IgG2b kappa

Clonality

Monoclonal

Concentration

1.0 mg/mL

Entrez Gene Id

7079,110595

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