logo
logo
Advertisehere
BMA Biomedicals Horizontal banner
BMA Biomedicals

Latest promotion FROM:

BMA Biomedicals
View promotion
Anti-TMEM64 polyclonal antibody

Cat no: DPABW1101

Anti-TMEM64 polyclonal antibody

Rabbit Anti-Human TMEM64 polyclonal antibody for ELISA, WB, IHC. Positively regulates TNFSF11-induced osteoclast differentiation. Acts as a regulator of TNFSF11-mediated Ca(2+) signaling pathways via its interaction with SERCA2 which is critical for the TNFSF11-induced CREB1 activation and mitochondrial ROS generation necessary for proper osteoclast generation. Association between TMEM64 and SERCA2 in the ER leads to cytosolic Ca (2+) spiking for activation of NFATC1 and production of mitochondrial ROS, thereby triggering Ca (2+) signaling cascades that promote osteoclast differentiation and activation. Negatively regulates osteoblast differentiation and positively regulates adipocyte differentiation via modulation of the canonical Wnt signaling pathway. Mediates the switch in lineage commitment to osteogenesis rather than to adipogenesis in mesenchymal stem cells by negatively regulating the expression, activity and nuclear localization of CTNNB1.

Prices direct from Creative Diagnostics

Quick response times

Exclusive Biosave savings/discounts

SPECIFICATIONS

Catalog Number

DPABW1101

Applications

ELISA

Hosts

Rabbit

Reactivities

Hum, Mouse

Target

TMEM64

Gene Id

169200

Isotype

IgG

Clonality

Polyclonal

Storage Temp

Upon delivery aliquot and store at -20В°C or -80В°C. Avoid repeated freeze.

SUPPLIER INFO

Creative Diagnostics

Applications

ELISA

Hosts

Rabbit

Reactivities

Hum

Conjugates

Unconj

More info

Hosts

Mouse

Reactivities

Hum

Conjugates

Unconj

More info

Hosts

Rabbit

Reactivities

Hum

Conjugates

Unconj

More info

Hosts

Mouse

Reactivities

Hum

Conjugates

Unconj

More info

Hosts

Rabbit

Reactivities

Hum

Conjugates

Unconj

More info

Hosts

Rabbit

Reactivities

Hum

Conjugates

Unconj

More info

Hosts

Rabbit

Reactivities

Hum

Conjugates

Unconj

More info

Hosts

Rabbit

Reactivities

Hum

Conjugates

Unconj

More info

Latest promotions

Spend less time on DNA cleanup so you can do more science. The MSB Spin PCRapace is the fastest way to purify your DNA from PCR, restriction digestion, and...

As an incentive to qualify our BSA, we are offering a 20% discount when you purchase your first 100g, 500g or 1000g of any grade of Bovine Serum Albumin....

New brilliant antibodies, and new lower prices!For flow cytometry reagents in general, \"bright is better.\" The violet-excitable BD Horizon™ BV421 and...

It is not every day that you are given something for nothing. We are giving away additional spectrophotometer software.Cecil Instruments have enhanced the...

Did your supplier increase the price of Fetal Bovine Serum? Did they substitute the US Origin with USDA? Well say no more! Innovative Research is still...

We're so sure that you'll prefer Cayman Assay kits over your present brand that we're willing to give you a free assay kit to prove it!

For the past decade scientists have extensively used ATS secondary toxin conjugates to make their own targeted toxins for in vitro use.The ability to combine...

10% Discount on 2 Rabbit Polyclonal Antibody Service. With over 20 years experience, SDIX has developed into the premier US custom antibody producer,...

Bulk Cytokines with Custom Vialing.20 - 50% off cytokines, growth factors, chemokines and more...For a limited time Cell Sciences is offering substantial...

Are you planning to have a customised antibody made for your research?Since 2000, Everest has been producing a catalog containing thousands of affinity...

Jenway’s 73 series spectrophotometer range provides four models with a narrow spectral bandwidth of 5nm and an absorbance range of –0.3 to 2.5A,...