Rabbit anti-?-Tocopherol polyclonal antibody. ?-Tocopherol is a form of vitamin E that is preferen- tially absorbed and accumulated in humans. The mea- surement of "vitamin E" activity in international units (IU) was based on fertility enhancement by the pre- vention of spontaneous abortions in pregnant rats relative to alpha-tocopherol. There are three stereoc- enters in alpha-tocopherol, so this is a chiral molecule. The eight stereoisomers of alpha-tocopherol differ in the arrangement of groups around these stereocen- ters. In the image of RRR-alpha-tocopherol, all three stereocenters are in the R form. However, if the middle of the three stereocenters were changed (so the hydr- ogen was now pointing down and the methyl group pointing up), this would become the structure of RSR- alpha-tocopherol. RSR-alpha-tocopherol and RRR- alpha-tocopherol are diastereomers of each other. These stereoisomers can also be named in an alterna- tive older nomenclature, where the stereocenters are either in the d or l form.
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