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Anti-TRAF3 polyclonal antibody

Cat no: CABT-B1601

Anti-TRAF3 polyclonal antibody

Rabbit Anti-Human TRAF3 polyclonal antibody for WB, ICC. TNF receptor-associated factor 3 (TRAF3) has many alternative names including CAP-1, CD40 receptor-associated factor 1(CRAF1), CD40-binding protein(CD40BP) and LMP1-associated protein 1 (LAP1). TRAF3 regulates pathways leading to the activation of NF-kappa-B and MAP kinases, and plays a central role in the regulation of innate immune response. It modulates signaling pathways leading to the production of cytokines and interferon. As an essential constituent of several E3 ubiquitin-protein ligase complexes, TRAF3 promote Lys-63-linked ubiquitination of target proteins. Moreover, TRAF3 undergoes both Lys-48-linked and Lys-63-linked ubiquitination in response to various stimuli and is deubiquitinated by OTUB1, OTUB2 and OTUD5.

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SPECIFICATIONS

Catalog Number

CABT-B1601

Hosts

Rabbit

Reactivities

Hum

Target

TRAF3

Gene Id

7187

Clonality

Polyclonal

Storage Temp

Stable for 1 year at 2-8В°C from date of receipt.

SUPPLIER INFO

Creative Diagnostics

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