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anti-Tumor Necrosis Factor (TNF) antibody

Cat no: ABIN1043796

anti-Tumor Necrosis Factor (TNF) antibody

anti-Tumor Necrosis Factor (TNF) antibody: Anti TNF alpha Antibody recognizes TNF alpha (TNF, cachexin, cachectin, tumor necrosis factor-alpha or TNF-alpha) a cytokine involved in systemic inflammation. TNF alpha is a member of a group of cytokines that stimulate the acute phase reaction. It is produced chiefly by activated macrophages, although it can be produced by other cell types as well. The primary role of TNF alpha is in the regulation of immune cells. TNFis an endogenous pyrogen that is able to induce fever, apoptotic cell death, sepsis (through IL-1 & IL-6 production), cachexia, inflammation, and to inhibit tumorigenesis and viral replication. Dysregulation of TNF production has been implicated in a variety of human diseases, including Alzheimer's disease, cancer, major depression, and inflammatory bowel disease (IBD).

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SPECIFICATIONS

Catalog Number

ABIN1043796

Size

25 micro L

Applications

BNI, ELISA, IHC, WB

Hosts

Rabbit

Reactivities

Hum

Antigen

TNF alpha

Gene Id

7124

Isotype

IgG

Accession

P01375

Clonality

Polyclonal

Concentration

1.0 mg/mL

Entrez Gene Id

7124

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