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Anti-XTP4 (aa66-83) polyclonal antibody

Cat no: CABT-B942

Anti-XTP4 (aa66-83) polyclonal antibody

Rabbit Anti-Human XTP4 polyclonal antibody for ELISA, WB. Certain loci on human chromosome 17q12 are frequently amplified in various types of cancers. One of such loci is PP1R1B-ERBB2-GRB7 which is greatly amplified in gastric and breast cancer. Search of other genes that reside close to this recombination hot spot or ""fragile loci"" led to discovery of several genes, one of these genes is a new theoretical protein MGC14832 is localized on chromosome 17 at cytogenetic location of 17q21.2. The detailed analyses of the amplicon structure in 330 breast tumors samples revealed a 280 kb common region of amplification that contains 10 genes that include 8 known genes. A highly significant association between amplification and expression levels was observed for 6 genes including ERBB2 and 2 uncharacterized hypothetical proteins, MGC9753 and MGC14832, in breast carcinoma and human gastric cancer samples. MGC14832 is located on human chromosome 17q12 and is in the amplicon cluster consist of PPP1R1B-STARD3-TCAP-PNMT-MGC9753-ERBB2-MGC14832-GRB7 with in the 120 kb region locus on human chromosome 17q12.

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SPECIFICATIONS

Catalog Number

CABT-B942

Applications

ELISA

Hosts

Rabbit

Reactivities

Hum, Mouse, Rat

Conjugates

Unconj

Target

MIEN1

Isotype

IgG

Clonality

polyclonal

Storage Temp

Keep as concentrated solution. Store at 4В°C short term. For extended storage aliquot and store at -20В°C or below. Avoid freeze-thaw cycles.

SUPPLIER INFO

Creative Diagnostics

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