Sheep anti-Zopiclone polyclonal antibody for IA, ELISA, WB, Dot, IHC. Zopiclone (brand name Imovane in Canada, Australia and Zimovane in the UK) is a non-benzodiazepine hypnotic (a cyclopyrrolone, which increases the normal transmission of the signal substance GABA in the central nerve system, as benzodiazepines do, however in a rather different way) agent used in the treatment of insomnia. In the United States, zopiclone is not commercially available, although its active stereoisomer, eszopiclone, is sold under the name Lunesta (see History). Zopiclone is a controlled substance in the United States, Japan, Brazil and some European countries, and may be illegal to possess without a prescription.