ANXA9, ID (ANXA9, ANX31, Annexin A9, Annexin XXXI, Annexin-31, Annexin-9, Pemphaxin) (PE)

The annexins are a family of calcium-dependent phospholipid-binding proteins. Members of the annexin family contain 4 internal repeat domains, each of which includes a type II calcium-binding site. The calcium-binding sites are required for annexins to aggregate and cooperatively bind anionic phospholipids and extracellular matrix proteins. This gene encodes a divergent member of the annexin protein family in which all four homologous type II calcium-binding sites in the conserved tetrad core contain amino acid substitutions that ablate their function. However, structural analysis suggests that the conserved putative ion channel formed by the tetrad core is intact.\n\nApplications:\nSuitable for use in Western Blot, ELISA\n\nRecommended Dilution:\nELISA: 1:1,000\nWestern Blot: 1:100-500\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Do not freeze R-Phycoerythrin conjugates. Light sensitive. Aliquots are stable for 6 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

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SPECIFICATIONS

Catalog Number

031932-PE

Size

200ul

Applications

ELISA, WB

Hosts

Rabbit

Reactivities

Hum

Form

Supplied as a liquid in PBS, pH 7.2. Contains ~0.09% sodium azide. Conjugated to R-Phycoerythrin (R-PE).

P Type

Pab

Purity

Purified by Protein A affinity chromatography.

Isotype

IgG

References

Kottgen, A., et al. Nat. Genet. 42(5):376-384(2010)\nBeausoleil, S.A., et al. Proc. Natl. Acad. Sci. U.S.A. 101(33):12130-12135(2004)\nGoebeler, V., et al. FEBS Lett. 546 (2-3), 359-364 (2003) :\nNguyen, V.T., et al. J. Biol. Chem. 275(38):29466-29476(2000)\nMorgan, R.O., et al. Gene 227(1):33-38(1999)

Additional Info

Human

Alternative Names

ANXA9, ANX31, Annexin A9, Annexin XXXI, Annexin-31, Annexin-9, Pemphaxin