Catalogue number: |
A2298-69F |
Reactivities: |
Human, Mouse, Rat |
Hosts: |
Mouse |
Applications: |
Immunofluorescence, Immunohistochemistry |
Size: |
50ug |
Form: |
0.1% Sodium Azide; 0.2% Gelatin, 0.05M Sodium phosphate |
P type: |
Mab |
Isotype: |
IgG2b |
Purity: |
Purified by immunoaffinity chromatography. |
Alternative names: |
Adenomatous Polyposis Coli, APC, DP2, DP2.5, DP3, FAP, FPC, GS |
References: |
Bhat RV et al. Expression of the APC tumor suppressor protein in oligodendroglia. Glia 17:169-74 (1996). Bhat RV et al. High levels of expression of the tumor suppressor gene APC during development of the rat central nervous system. J Neurosci 14:3059-71 (1994). Smith KJ et al. Wild-type but not mutant APC associates with the microtubule cytoskeleton. Cancer Res 54:3672-5 (1994). Smith KJ et al. The APC gene product in normal and tumor cells. Proc Natl Acad Sci U S A 90:2846-50 (1993). Su LK et al. Association between wild type and mutant APC gene products. Cancer Res 53:2728-31 (1993). Su LK et al. Association of the APC tumor suppressor protein with catenins. Science 262:1734-7 (1993). Groden J et al. Identification and characterization of the familial adenomatous polyposis coli gene. Cell 66:589-600 (1991). Kinzler KW et al. Identification of a gene located at chromosome 5q21 that is mutated in colorectal cancers. Science 251:1366-70 (1991). |
Additional info: |
This antibody has been shown to detect oligodendrocytes and astrocytes. Species Crossreactivity: Crossreacts with Human, Mouse and Rat. |