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APC anti-human Notch 2

APC anti-human Notch 2

Cat no: 348306

Supplier: BioLegend
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The Notch receptors are a type I transmembrane protein family that share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple, different domain types. They are highly conserved from invertebrates to mammals.Notch 1 and Notch 2 exhibit the highest structural similarity among the four mammalian Notch receptors (Notch 1-4). Notch 1 and Notch 2 are reported to be functionally redundant. Notch 2 is expressed by Pre-B cells, double negative, and CD8 single positive thymocytes, brain, and lung cells. Notch 2 functions as a receptor for Jagged and Delta ligands and may play a role in vascular, renal and hepatic development.
Catalogue number: 348306
Reactivities: Human
Hosts: Mouse
Applications: Flow Cytometry
Size: 100 tests
Clone: MHN2-25
Gene: 4853
Dilutions: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. Test size products are transitioning from 20 microl to 5 microl per test. Please check your vial or your CoA to find the suggested use of this reagent per million cells in 100 microl staining volume or per 100 microl of whole blood. It is recommended that the reagent be titrated for optimal performance for each application. Read more at www.biolegend.com/testsize regarding the test size change.
Storage buffer: The antibody solution should be stored undiluted at 4C and protected from prolonged exposure to light. Do not freeze.
Antigen: Human Notch 2-human IgG1 Fc fusion protein
Isotype: Mouse IgG2a, kappa
Clonality: Monoclonal
Regulatory status: RUO
Shipping temp: Ambient RT
Storage temp: 4 C
Alternative names: Neurogenic locus notch homolog protein 2, hN2, fN2
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