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APC anti-mouse CD133

APC anti-mouse CD133

Cat no: 141208

Supplier: BioLegend
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CD133 (also known as Prominin-1 or AC133) is a 120 kD pentaspan glycoprotein with 5 transmembrane domains which localize to cellular protrusions. CD133 was initially described as a surface antigen specific for human hematopoietic stem cells and as a marker for murine neuroepithelial cells and some embryonic epithelia. Later on, CD133 was found on other stem cells including endothelial progenitor cells, glioblastomas, neuronal, and glial stem cells. In addition to hematopoietic stem cells, CD133 was found on cancer cells, such as some leukemia cells and brain tumor cells. It also has been detected at low levels in the kidney, pancreas, placenta, and fetal liver tissue. Although the biological function of CD133 is not conclusive, CD133 has been extensively used as a stem cell marker for normal and cancerous tissues.
Catalogue number: 141208
Reactivities: Mouse
Hosts: Rat
Applications: Flow Cytometry
Size: 100 microg
Clone: 315-2C11
Gene: 19126
Dilutions: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is ?0.25 microg per million cells in 100 microl volume. It is recommended that the reagent be titrated for optimal performance for each application.
Storage buffer: The antibody solution should be stored undiluted at 4C and protected from prolonged exposure to light. Do not freeze.
Concentration: 0.2 mg/ml
Antigen: CD133-expressing-GFP-RBL2H3 plus CFA as adjuvant.
Isotype: Rat IgG2a, lambda
Clonality: Monoclonal
Regulatory status: RUO
Shipping temp: Ambient RT
Storage temp: 4 C
Alternative names: Prominin-1, AC133
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