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APC anti-mouse/rat CD61

APC anti-mouse/rat CD61

Cat no: 104315


Supplier: BioLegend
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CD61 is a 110 kD integrin beta chain also known as beta3 integrin or gpIIIa. It associates with the integrin alphav chain (CD51) to form the vitronectin receptor. In addition, CD61 can associate with the integrin alphaIIb chain (CD41) to form the gpIIb/IIIa complex. CD61 is expressed on platelets, megakaryocytes, endothelium, smooth muscle, a subset of B cells, myeloid cells, osteoclasts, and mast cells. CD61, in conjunction with CD41 or CD51, mediates adhesion to fibronectin, fibrinogen, vitronectin, thrombospondin, and von Willebrand factor. Leukocyte-endothelial adhesion is mediated by the binding of alphav/beta3 integrin or vitronectin receptor to CD31 (PECAM-1).
Catalogue number: 104315
Reactivities: Mouse, Rat
Hosts: Hamster
Applications: Flow Cytometry
Size: 25 microg
Clone: 2C9.G2 (HMbeta3-1)
Gene: 16416,29302
Dilutions: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is ?0.5 microg per million cells in 100 microl volume. It is recommended that the reagent be titrated for optimal performance for each application.
Storage buffer: The antibody solution should be stored undiluted at 4C and protected from prolonged exposure to light. Do not freeze.
Concentration: 0.2 mg/ml
Antigen: Vitronectin receptor protein from the mouse T-cell hybridoma 2B4.
Isotype: Armenian Hamster IgG
Clonality: Monoclonal
Regulatory status: RUO
Shipping temp: Ambient RT
Storage temp: 4 C
Alternative names: beta3 integrin, Integrin beta3 chain, gpIIIa
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