Home  >  Products  >  APC6 (Anaphase Promoting Complex 6, ANAPC6, APC 6, Cell Division Cycle 16 Homolog, Cell Division Cycle Protein 16 Homolog, CDC16, CDC16Hs, Cyclosome Subunit 6)
APC6 (Anaphase Promoting Complex 6, ANAPC6, APC 6, Cell Division Cycle 16 Homolog, Cell Division Cycle Protein 16 Homolog, CDC16, CDC16Hs, Cyclosome Subunit 6)

APC6 (Anaphase Promoting Complex 6, ANAPC6, APC 6, Cell Division Cycle 16 Homolog, Cell Division Cycle Protein 16 Homolog, CDC16, CDC16Hs, Cyclosome Subunit 6)

Cat no: A2298-72L4

Supplier: United States Biological
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CDC16 is located at the centrosome and mitotic spindle where it co-localizes with CDC27 and is required for maintaining core stability in the spindle checkpoint pathway. It functions as a component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. Applications: Suitable for use in ELISA, Immunohistochemistry (paraffin), and Western Blot. Other applications not tested. Recommended Dilution: Immunohistochemistry (paraffin): 5ug/ml ELISA: 1:10,000 Western Blot: 1:500-1:3,000 Requires antigen retrieval using heat treatment for 20 minutes prior to staining of paraffin sections. Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile 40-50% glycerol, aliquot and store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: A2298-72L4
Reactivities: Human
Hosts: Rabbit
Applications: ELISA, Immunohistochemistry, Western Blot
Size: 50ug
Form: Supplied as a liquid in PBS, pH 7.2, 0.01% sodium azide.
P type: Pab
Isotype: IgG
Purity: Purified by immunoaffinity chromatography.
Alternative names: Anaphase Promoting Complex Subunit 6, CDC16 (Cell Division Cycle 16 S. cerevisiae Homolog), CDC16 Protein
Additional info: Recognizes human CDC16.

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