APE-1 (Apurinic Endonuclase Factor 1)

Cat no: A2298-74E1

Supplier: United States Biological

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APE1 repairs oxidative DNA damages in vitro. It may also play a role in preventing cell death by suppressing mutations. APE1 removes the blocking groups from the 3'-termini of breaks in the DNA strand generated by ionizing radiation or bleomycin. APE1 is part of the cellular response to oxidative stress and protects cells from the genotoxic and cytotoxic effects of oxidizing agents. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: ELISA: 0.05-0.2ug/ml Western Blot: 0.5-1ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized powder may be stored at -20 degrees C. Reconstitute with sterile 40-50% glycerol, aliquot and store at -20 degrees C. Reconstituted product is stable for 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Catalogue number:	A2298-74E1
Reactivities:	Human
Hosts:	Rabbit
Applications:	ELISA, Western Blot
Size:	40ug
Form:	Supplied as a lyophilized powder in PBS, pH 7.4, 0.02% sodium azide.
P type:	Pab
Isotype:	IgG
Purity:	Purified by immunoaffinity chromatography.
Additional info:	Recognizes endogenous levels of human APE1 protein.

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APE-1 (Apurinic Endonuclase Factor 1)

Cat no: A2298-74E1

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