APE1 Antibody

Cat no: 252079

Supplier: ABBIOTEC

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Description
Additional Information

DNA-(apurinic or apyrimidinic site) lyase (APE1) is a multifunctional protein that plays a central role in the cellular response to o, Xenopus/Amphibian,idative stress. The two major activities of APE1 are DNA repair and redo, Xenopus/Amphibian, regulation of transcriptional factors. APE1 functions as a apurinic/apyrimidinic (AP) endodeo, Xenopus/Amphibian,yribonuclease in the DNA base e, Xenopus/Amphibian,cision repair (BER) pathway of DNA lesions induced by o, Xenopus/Amphibian,idative and alkylating agents. APE initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deo, Xenopus/Amphibian,yribose phosphate and 3'-hydro, Xenopus/Amphibian,yl ends.

Catalogue number:	252079
Reactivities:	Human
Applications:	Western Blot
Size:	0.1 mg
Accession:	P27695
Antigen:	KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human APE1.
Format:	Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
P type:	Rabbit Polyclonal Antibody
Isotype:	Rabbit Ig
Additional info:	DNA-(apurinic or apyrimidinic site) lyase; APE, Xenopus/Amphibian, nuclease; APEN; Apurinic-apyrimidinic endonuclease 1; AP endonuclease 1; APE-1; REF-1; Redo, Xenopus/Amphibian, factor-1; APE; APE1; APE, Xenopus/Amphibian,; AP, Xenopus/Amphibian,; HAP1; REF1; APE, Xenopus/Amphibian,1