Apilimod

Cat no: 002800

Supplier: United States Biological

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Apilimod is a small-molecule that selectively suppresses synthesis of IL-12 and IL-23. Apilimod reduces dendritic cell infiltration in psoriasis. Melting Point: As Reported Solubility: As Reported Method for Determining Identity: Proton NMR (DMSO-d6) Spectroscopic and Mass Spectrometric Analysis TLC Conditions: As Reported Elemental Analysis: As Reported Storage and Stability: May be stored at RT for short-term only. Long-term storage is recommended at 4 degrees C. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. Toxicity and Hazards:

Catalogue number:	002800
Size:	100mg
Form:	As Reported
Purity:	~90%
Alternative names:	3-Methylbenzaldehyde 2-[6-(4-Morpholinyl)-2-[2-(2-pyridinyl)ethoxy]-4- pyrimidinyl]hydrazone; STA 5326;
References:	1. Lebwohl, M., et al.: Lancet, 361, 1197 (2003). 2. Gottlieb, A., et al.: J. Immunol ., 175, 2721 (2005). 3. Chan, J., et al.: J. Exp. Med., 203, 2577 (2006). 4. Kryczek, I., et al.: J. Immunol., 181, 4733 (2008). 5. Gottlieb, A., et al.: Br. J. Dermatol., 165, 652 (2001)

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Apilimod

Cat no: 002800

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