APJ Receptor (APLNR, Apelin receptor, AGTRL1, angiotensin II receptor-like 1, Angiotensin receptor-like 1, Apelin receptor, APJ, APJR, FLJ90771, G-protein coupled receptor APJ, HG11, MGC45246)

The apelin receptor (APJ receptor) has been identified as the endogenous receptor for the the peptide apelin. Previous to the identification of apelin, APJ was considered an orphan G protein coupled receptor. The apelin receptor (both by immunohistochemistry and in situ) has been localized to the CNS and is currently thought to play a role in stress response, feeding behavior and haemodynamic homeostasis. However, because of a broad distribution the apelin receptor and its endogenous ligand be involved in a wide range of biological process yet to be determined.\n\nSequence (linear): (Cys)-TIAGHFRKERIEGLRK-amide\nSee corresponding antibody A2298-80.\n\nApplications: \nSuitable for use in ELISA. Other applications not tested.\n\nRecommended Dilution:\nOptimal dilutions to be determined by the researcher.\n\nStorage and Stability: \nLyophilized powder may be stored at 4 degrees C for short-term only. Stable for 12 months at -20 degrees C. Reconstitute to nominal volume (see reconstitution instructions for peptides) and store at -20 degrees C. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer.\n\nPeptide Reconstitution Instructions:\nThe solubility of peptides depends on the primary structure of the molecule. While most dissolve freely in aqueous media, there are many examples of poor solubility, especially when peptides that contain an excess of hydrophobic residues. Unless you know that the peptide is freely soluble in your intended solvent, we recommend the following procedure:\nAdd a small amount of sterile, distilled water. If the peptide does not dissolve, sonication may help. Alternatively, or subsequently, add a small volume of 10% aqueous acetic acid (for basic peptides) or aqueous ammonia (for acidic peptides). Once the peptide is dissolved, buffer or salt solution may be added to obtain the desired concentration. Sterile filter the final stock solution. Peptides are more stable under acidic conditions and we recommend a choice of pH between 3.0 and 6.0.\nIf still unable to dissolve:\n1. Hydrophobic peptides: Try 1mg in 1ml deionized water and vortex, then add DMF drop by drop and vortex until dissolved.\n2. Basic peptides: Try 1% acetic acid solution. If peptide still doesn

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SPECIFICATIONS

Catalog Number

A2298-80A

Size

1mg

Applications

ELISA

Form

Supplied as a lyophilized powder.

Purity

Highly Purified

Alternative Names

APLNR, Apelin receptor, AGTRL1, angiotensin II receptor-like 1, Angiotensin receptor-like 1, Apelin receptor, APJ, APJR, FLJ90771, G-protein coupled receptor APJ, HG11, MGC45246