Apo-E Antibody

Cat no: 250544

Supplier: ABBIOTEC

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Description
Additional Information

Apolipoprotein E (Apo-E) is a protein component of plasma lipoprotein that mediates the binding, internalization and catabolism of lipoprotein particles. Apo-E can serve as a ligand for the LDL (Apo-B/E) receptor and for the specific Apo-E receptor (chylomicron remnant) of hepatic tissues. Apo-E is present in all lipoprotein fractions in plasma and constitutes 10-20% of very low density lipoproteins (VLDL) and 1-2% of high density lipoproteins (HDL) . Apo-E is produced in most organs. Defects in Apo-E are a cause of hyperlipoproteinemia type III (lipid deposits in palms, tendons and elbows), sea-blue histiocyte disease (splenomegaly, thrombocytopenia), and lipoprotein glomerulopathy.

Catalogue number:	250544
Reactivities:	Rabbit
Applications:	Immunohistochemistry
Size:	0.1 mg
Accession:	P02649
Antigen:	KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of mouse Apo-E.
Format:	Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
P type:	Rabbit Polyclonal Antibody
Isotype:	Rabbit Ig
Additional info:	Apolipoprotein E; Apo-E; APOE