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APPL2 (DCC-interacting Protein 13-beta, Dip13-beta, Adapter Protein Containing PH Domain, PTB Domain and Leucine Zipper Motif 2, DIP13B)

APPL2 (DCC-interacting Protein 13-beta, Dip13-beta, Adapter Protein Containing PH Domain, PTB Domain and Leucine Zipper Motif 2, DIP13B)

Cat no: A0859-44P

Supplier: United States Biological
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APPL2, also termed as Adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2, has been shown to be involved in the regulation of cell proliferation, and in the crosstalk between the adiponectin signalling and insulin signalling pathways. The encoded protein binds many other proteins, including RAB5A, APPL1, adiponectin receptors, and proteins of the NuRD/MeCP1 complex. Applications: Suitable for use in ELISA, Western Blot, Immunoprecipitation, and Immunohistochemistry. Other applications not tested. Recommended Dilution: ELISA: 1-2ug/ml Western Blot: 0.2-0.3ug/ml Immunohistochemistry: 2-3ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: A0859-44P
Reactivities: Human, Mouse, Rat, Non-Human Primate
Hosts: Rabbit
Applications: ELISA, Immunohistochemistry, Immunoprecipitation, Western Blot
Size: 100ug
Form: Supplied as a liquid in 10mM sodium HEPES, pH 7.5, 150mM sodium chloride, BSA.
P type: Pab
Isotype: IgG
Purity: Purified by immunoaffinity chromatography.
Additional info: Recognizes human APPL2. Species Cross-Reactivity: monkey, mouse, rat.

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