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Aprataxin (APTX)

Cat no: A2299-97D


Supplier: United States Biological
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This gene encodes a member of the histidine triad (HIT) superfamily, some of which have nucleotide-binding and diadenosine polyphosphate hydrolase activities. The encoded protein may play a role in single-stranded DNA repair. Mutations in this gene have been associated with ataxia-ocular apraxia. Multiple transcript variants encoding distinct isoforms have been identified for this gene, however, the full length nature of some variants has not been determined. Applications: Suitable for use in Western Blot and Immunoprecipitation,. Other applications not tested. Recommended Dilution: Immunoprecipitation: 1-4ug/mg lysate Western Blot: 1:10,000- 1:25,000 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: A2299-97D
Reactivities: Human
Hosts: Rabbit
Applications: Immunoprecipitation, Western Blot
Size: 100ul
Form: As reported
P type: Pab
Purity: Purified by immunoaffinity chromatography.
Alternative names: AOA1, Ataxia-oculomotor apraxia syndrome 1, FHA-HIT, Forkhead-associated domain histidine-triad like protein, EOAHA, early onset with hypoalbuminemia
Additional info: Recognizes human Aprataxin protein. Reaction with mouse is unlikely.

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