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AQP2 (Ser261) Antibody
ABBIOTEC

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ABBIOTEC

Cat no: 252521

AQP2 (Ser261) Antibody

Aquaporin-2 (AQP-2) forms a water specific channel that provides the plasma membranes of renal collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient. It is e, Xenopus/Amphibian,pressed in the renal collecting tubules. Defects in AQP-2 are a cause of autosomal recessive nephrogenic diabetes insipidus (ANDI), also known as diabetes insipidus nephrogenic type 2. It is characterized by e, Xenopus/Amphibian,cessive water drinking (polydypsia) and urine e, Xenopus/Amphibian,cretion (polyuria). AQP-2 belongs to the MIP/aquaporin (TC1.A.8) family. Ser-256 phosphorylation is necessary and sufficient for e, Xenopus/Amphibian,pression at the apical membrane.

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SPECIFICATIONS

Catalog Number

252521

Size

0.1 ml

Applications

WB

Reactivities

Hum, Mouse, Bov, Ch/Bird

Format

Each vial contains 0.1 ml IgG in HEPES pH7.5, 150 mM NaCl, 0.01% BSA and 50% glycerol. Antibody was purified by immunogen affinity chromatography.

P Type

Rabbit Polyclonal Antibody,Porcinehosphospecific Antibody

Antigen

KLH-conjugated synthetic phosphopeptide encompassing a sequence surrounding Ser261 of human AQP2.

Isotype

Rabbit IgG

Accession

P34080

Additional Info

Aquaporin-2; AQP2; Aquaporin protein-2; AQP-2; Aquaporin-CD; AQP-CD; Water channel protein for renal collecting duct; ADH water channel; Collecting duct water channel protein; WCH-CD

SUPPLIER INFO

ABBIOTEC

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