AQP2 (Ser269) Antibody

Cat no: 252523

Supplier: ABBIOTEC

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Description
Additional Information

Aquaporin-2 (AQP-2) forms a water specific channel that provides the plasma membranes of renal collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient. It is e, Xenopus/Amphibian,pressed in the renal collecting tubules. Defects in AQP-2 are a cause of autosomal recessive nephrogenic diabetes insipidus (ANDI), also known as diabetes insipidus nephrogenic type 2. It is characterized by e, Xenopus/Amphibian,cessive water drinking (polydypsia) and urine e, Xenopus/Amphibian,cretion (polyuria). AQP-2 belongs to the MIP/aquaporin (TC1.A.8) family. Serine-269 has been identified as a vasopressin-mediated phosphorylation site on AQP2 and as such has shown to potentiate plasma membrane retention of AQP2.

Catalogue number:	252523
Reactivities:	Bovine
Applications:	Western Blot
Size:	0.1 ml
Accession:	P34080
Antigen:	KLH-conjugated synthetic phosphopeptide encompassing a sequence surrounding Ser264 of human AQP2.
Format:	Each vial contains 0.1 ml IgG in HEPES pH7.5, 150 mM NaCl, 0.01% BSA and 50% glycerol. Antibody was purified by immunogen affinity chromatography.
P type:	Rabbit Polyclonal Antibody,Porcinehosphospecific Antibody
Isotype:	Rabbit IgG
Additional info:	Aquaporin-2; AQP2; Aquaporin protein-2; AQP-2; Aquaporin-CD; AQP-CD; Water channel protein for renal collecting duct; ADH water channel; Collecting duct water channel protein; WCH-CD