Aquaporin 6 (WCH3, hKID, AQP2-L)\n

AQP6 (WCH3 or hKID or AQP2-like; 282 aa; 29kD; chromosome 12q13) is found only in the kidney with low water permeability. AQP families of proteins are predicted to contain six transmembrane domains. The N and C-terminus are predicted to be cytoplasmic. AQP6 shows greatest homology with hMIP (48%) and hAQP-2 (52%). It also has similarity with human MIWC (AQP4; 34%), CHIP-28 (AQP1; 38%), and GLIP (AQP3; 22%).\n\nApplications: \nSuitable for use in ELISA and Western Blot. Other applications not tested.\n\nRecommended Dilution\nWestern Blot: 1:1000-1:5000 using Chemiluminescence technique.\nELISA: 1:10,000-1:50,000. Coat ELISA plate with 1ug/ml control peptide.\nOptimal dilutions to be determined by the researcher.\n\nRecommended Control Peptide: \nA3000-25D: Aquaporin 6, Human, Control Peptide (WCH3, hKID, AQP2-L)\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

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SPECIFICATIONS

Catalog Number

A3000-26

Size

50ul

Applications

ELISA, WB

Hosts

Rabbit

Reactivities

Hum

Form

Supplied as a liquid in PBS, 0.05% sodium azide.

P Type

Pab

Purity

Serum

Isotype

IgG

References

1. Ma T et al (1996) Genomics 35, 543-550. 2. Jeremic A, 2005, Exp. Biol. Med 230: 674-680. 3. WAng, W, 2003 Calcified T. Intl 72(3): 222-227

Additional Info

Recognizes human Aquaporin 6. Epitope recognized by this antibody is not found in human AQP6 isoform 2. No significant homology to AQP2 or any other AQPs.