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(aR,bS)-rel-Bedaquiline

Cat no: 167222


Supplier: United States Biological
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(aR,bS)-rel-Bedaquiline is a promising diarylquinoline candidate in clinical development for the treatment of tuberculosis. (aR,bS)-rel-Bedaquiline inhibits mycobacterial ATP synthase and displays high activity against both drug-susceptible and multidrug-resistant strains of Mycobacterium tuberculosis. Melting Point: 181-183 degrees C Solubility: Chloroform, Ethyl Acetate
Catalogue number: 167222
Size: 5mg
Form: Supplied as a Off-white Solid to Pale Yellow Solid
Alternative names: (aR,bS)-rel-6-Bromo-a-[2-(dimethylamino)ethyl]-2-methoxy-a-1-naphthalenyl-b-phenyl-3-quinolineethanol
References: Guillemont, J. et al.: Fut. Med. Chem., 3, 1345 (2011); Koul, A. et al.: Nat. Chem. Biol., 3, 323 (2007)

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