ARG1 (Arg1, Arginase 1, AI type I arginase, arginase 1 liver)

Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exist (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type I isoform encoded by this gene, is a cytosolic enzyme and expressed predominantly in the liver as a component of the urea cycle. Inherited deficiency of this enzyme results in argininemia, an autosomal recessive disorder characterized by hyperammonemia.\n\nApplications:\nSuitable for use in ELISA and Western Blot. Other applications not tested.\n\nRecommended Dilution: \nELISA: 1:32,000\nWestern Blot: 0.01-0.03ug/ml\nOptimal dilution to be determined by researcher.\n\nPositive Controls: \nRat Liver lysate\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add 40-50% glycerol, aliquot and store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

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SPECIFICATIONS

Catalog Number

A3340-14B

Size

100ug

Applications

ELISA, WB

Hosts

Goat

Reactivities

Mouse, Rat

Form

Supplied as a liquid in tris-saline pH7.3 with 0.5% BSA, 0.02% sodium azide.

P Type

Pab

Purity

Purified by immunoaffinity chromatography

Isotype

IgG

References

Jiang M, Ding Y, Su Y, Hu X, Li J, Zhang Z. Arginase-flotillin interaction brings arginase to red blood cell membrane. FEBS Lett. 2006 Dec 11;580(28-29):6561-4. Epub 2006 Nov 13. PMID: 17113085.

Additional Info

Recognizes rat and mouse Arg1.