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Arginyl-tRNA Synthetase (RARS, MGC8641, DALRD1, ArgRS, arginyl-tRNA synthetase, arginine tRNA ligase 1, cytoplasmic)

Cat no: A3570-25


Supplier: United States Biological
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Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Arginyl-tRNA synthetase belongs to the class-I aminoacyl-tRNA synthetase family. Applications: Suitable for use in ELISA and Western Blot. Other applications have not been tested. Recommended Dilutions: Peptide ELISA Titer: 1:128,000 Western Blot: 1-3ug/ml ~75kD band observed in lysates of HeLa and HepG2 (calculated MW of 75.4kD according to NP_002878.2). Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: A3570-25
Reactivities: Human
Hosts: Goat
Applications: ELISA, Western Blot
Size: 100ug
Form: Supplied as a liquid in Tris saline, pH 7.3, 0.5% BSA, 0.02% sodium azide.
P type: Pab
Isotype: IgG
Purity: Purified by peptide affinity chromatography.
Alternative names: RARS, MGC8641, DALRD1, ArgRS, arginyl-tRNA synthetase, arginine tRNA ligase 1, cytoplasmic
References: 1. Bottoni A, Vignali C, Piccin D, Tagliati F, Luchin A, Zatelli MC, Uberti EC, Proteasomes and RARS modulate AIMP1/EMAP II secretion in human cancer cell lines. Journal of cellular physiology 2007 Aug 212 (2): 293-7.
Additional info: Recognizes human Arginyl-tRNA Synthetase. Species sequence homology: mouse, rat, bovine.

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