ARHGAP22 (R595) pAb

Cat no: BS3391

Supplier: Bioworld Technology, Inc.

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Description
Additional Information

GTPase-activating proteins (GAPs) accelerate the intrinsic rate of GTP hydrolysis of Ras-related proteins, resulting in down regulation of their active form. ARHGAP22 (Rho GTPase activating protein 22), also known as RHOGAP2, is a 698 amino acid protein that localizes to the cytoplasm, and contains one Rho-GAP domain and one PH domain. ARHGAP22 functions as a GTPase-activating protein for Rac 1 converting it to an inactive GDP-bound state and, through its interaction with ZNF161 (VEZF1), is thought to be useful in transcription regulation. Multiple isoforms of ARHGAP22 exist due to alternative splicing events.

Catalogue number:	BS3391
Reactivities:	Human, Mouse, Rat
Hosts:	Rabbit
Applications:	Western Blot
Size:	100ug/100ul
Swiss prot:	Q7Z5H3
Dilutions:	WB: 1:500~1:1000
Form:	liquid
Storage buffer:	1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration:	1ug/ul
Antigen:	Synthetic peptide, corresponding to amino acids 564-620 of Human ARHGAP22.
Species:	ARHGAP22 (R595) pAb detects endogenous levels of ARHGAP22 protein.
Molecular weight:	~ 77 kDa
Purity:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp:	Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names:	Rho GTPase-activating protein 22; Rho-type GTPase-activating protein 22; ARHGAP22; RHOGAP2
Additional info:	For research use only, not for use in diagnostic procedure.

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ARHGAP22 (R595) pAb

Cat no: BS3391

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