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ARHGAP22 (R595) pAb

Cat no: BS3391

ARHGAP22 (R595) pAb

GTPase-activating proteins (GAPs) accelerate the intrinsic rate of GTP hydrolysis of Ras-related proteins, resulting in down regulation of their active form. ARHGAP22 (Rho GTPase activating protein 22), also known as RHOGAP2, is a 698 amino acid protein that localizes to the cytoplasm, and contains one Rho-GAP domain and one PH domain. ARHGAP22 functions as a GTPase-activating protein for Rac 1 converting it to an inactive GDP-bound state and, through its interaction with ZNF161 (VEZF1), is thought to be useful in transcription regulation. Multiple isoforms of ARHGAP22 exist due to alternative splicing events.

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SPECIFICATIONS

Catalog Number

BS3391

Size

100ug/100ul

Applications

WB

Hosts

Rabbit

Reactivities

Hum, Mouse, Rat

Form

liquid

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Antigen

Synthetic peptide, corresponding to amino acids 564-620 of Human ARHGAP22.

Species

ARHGAP22 (R595) pAb detects endogenous levels of ARHGAP22 protein.

Dilutions

WB: 1:500~1:1000

Swiss Prot

Q7Z5H3

Storage Temp

Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.

Concentration

1ug/ul

Storage Buffer

1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.

Additional Info

For research use only, not for use in diagnostic procedure.

Molecular Weight

~ 77 kDa

Alternative Names

Rho GTPase-activating protein 22; Rho-type GTPase-activating protein 22; ARHGAP22; RHOGAP2

SUPPLIER INFO

Bioworld Technology, Inc.

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