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ARHGAP35 (Rho GTPase-activating Protein 35, Glucocorticoid Receptor DNA-binding Factor 1, Glucocorticoid Receptor Repression Factor 1, GRF-1, Rho GAP p190A, p190-A, GRF1, GRLF1, KIAA1722)

Cat no: 123487

ARHGAP35 (Rho GTPase-activating Protein 35, Glucocorticoid Receptor DNA-binding Factor 1, Glucocorticoid Receptor Repression Factor 1, GRF-1, Rho GAP p190A, p190-A, GRF1, GRLF1, KIAA1722)

Represses transcription of the glucocorticoid receptor by binding to the cis-acting regulatory sequence 5'-GAGAAAAGAAACTGGAGAAACTC-3'. May participate in the regulation of retinal development and degeneration. May transduce signals from p21-ras to the nucleus, acting via the ras GTPase-activating protein (GAP). May also act as a tumor suppressor.\n\nApplications:\nSuitable for use in ELISA. Other applications not tested.\n\nRecommended Dilution:\nOptimal dilutions to be determined by the researcher.\n\nAA Sequence:\nMEATSRSVHGDVGEVGHFEGMAVCWCPRRGILPGLR\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

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SPECIFICATIONS

Catalog Number

123487

Size

100ug

Applications

ELISA

Hosts

Mouse

Reactivities

Hum

Form

Supplied as a liquid in PBS, pH 7.2.

P Type

Mab

Purity

Purified by Protein A affinity chromatography.

Isotype

IgG2a,k

Additional Info

Recognizes human GRLF1.

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