ARL15, belongs to the ARF family. ARFs are important in eukaryotic vesicular trafficking pathways and play an essential role in the activation of phospholipase D. ARL15 variants influence levels of Acrp30, an adipocyte-derived protein that is particularly heritable and inversely associated with risk of type 2 diabetes mellitus and coronary heart disease.
Source:
Recombinant corresponding to aa1-204 from human ARL15, fused to His-tag at N-terminal expressed in E.coli.
AA Sequence:
MGSSHHHHHH SSGLVPRGSH MSDLRITEAF LYMDYLCFRA LCCKGPPPAR PEYDLVCIGL TGSGKTSLLS KLCSESPDNV VSTTGFSIKA VPFQNAILNV KELGGADNIR KYWSRYYQGS QGVIFVLDSA SSEDDLEAAR NELHSALQHP QLCTLPFLIL ANHQDKPAAR SVQEIKKYFE LEPLARGKRW ILQPCSLDDM DALKDSFSQL INLLEEKDHE AVRM
Molecular Weight:
~25kD (MALDI-TOF)
Storage and Stability:
May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.