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ASH1 (MASH1, Helix-loop-helix Transcription Factor, Achaete-scute Complex Homolog-like1, ASCL1)

ASH1 (MASH1, Helix-loop-helix Transcription Factor, Achaete-scute Complex Homolog-like1, ASCL1)

Cat no: A3782-02B

Supplier: United States Biological
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This protein plays a role in neuronal commitment and differentiantion in most regions of the CNS and of several neuronal lineages in the PNS. It is also essential for the generation of olfactory and autonomic neurons. The unprocessed precursor is 236 amino acids in length and 25.45KDa. ASCL1 contains one basic helix-loop-helix (bHLH) domain. It activates transcription by binding to the Ebox (5'-CANNTG-3') and efficient DNA binding requires dimerisation with other bHLH proteins. It forms a heterodimer with TCF3. Applications: Suitable for use in Western Blot and ELISA. Other applications not tested. Recommended Dilution: Optimal dilution determined by the researcher. Storage and Stability: Lyophilized powder may be stored at -20 degrees C. Stable for 12 months at -20 degrees C. Reconstitute with sterile 40-50% glycerol, ddH2O. Reconstituted product is stable for 12 months at -20 degrees C. Aliquot and store at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: A3782-02B
Reactivities: Human
Hosts: Mouse
Applications: ELISA, Western Blot
Size: 100ug
Form: Supplied as a lyophilized powder from PBS, pH 7.2, 150mM sodium chloride. Reconstitute with 100ul sterile ddH2O.
P type: Mab
Isotype: IgG
Purity: Purified by affinity chromatography.
Alternative names: Achaete-scute homolog 1, HASH1, GENE NAME: ASCL1, ASH1
Additional info: Recognizes human ASH1.

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