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ASM Peptide

ASM Peptide

Cat no: BS60373P

Supplier: Bioworld Technology, Inc.
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Acid sphingomyelinase (ASM) is a lysosomal protein that hydrolyzes sphingomyelin to ceramide and phosphocholine. The ASM gene encodes three proteins, ASM-1, ASM-2 and ASM-3, of which ASM-1 is the only ASM gene product that is a catalytically active enzyme. Deficiency of ASM is associated with type A and type B Niemann-Pick disease. Type A is a fatal neurodegenerative disorder seen in infancy and resulting in death by age three, whereas type B is a non-neuropathic disease that has a later onset. During monocytic cell differentiation, the expression of ASM is upregulated by the combined actions of AP-2 and Sp1 transcription factors.
Catalogue number: BS60373P
Applications: Block/Neutralize/Inhibit
Swiss prot: P17405
Form: 1 mg/ml in DI water.
Purity: Synthetic peptide ASM. (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names: Sphingomyelin phosphodiesterase; Acid sphingomyelinase; aSMase; SMPD1
Additional info: This peptide can be used with studies using BS60373 ASM pAb.

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