Home  >  Products  >  ASPP1 (ASPP-1, Apoptosis-Stimulated Protein of p53 Protein 1, PPP1R13B, Protein Phosphatase 1, Regulatory Subunit 13Bp53BP1-like, p85)
ASPP1 (ASPP-1, Apoptosis-Stimulated Protein of p53 Protein 1, PPP1R13B, Protein Phosphatase 1, Regulatory Subunit 13Bp53BP1-like, p85)

ASPP1 (ASPP-1, Apoptosis-Stimulated Protein of p53 Protein 1, PPP1R13B, Protein Phosphatase 1, Regulatory Subunit 13Bp53BP1-like, p85)

Cat no: A3883-50A

Supplier: United States Biological
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The ASPP family members ASPP1, ASPP2, act as potent activators of p53. A third member of the family, iASPP, has an inhibitory effect on apoptosis. The three members of ASPP family all bind p53 via their C-terminus, which contains a proline-rich region, four ankyrin repeats and an SH3 domain. Expression of ASPP1 and ASPP2 is frequently downregulated in human breast tumors expressing wild-type p53. ASPP1 may also play a role in vascular development. Applications: Suitable for use in Western Blot and Immunoprecipitation. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: A3883-50A
Reactivities: Human
Hosts: Rabbit
Applications: Immunoprecipitation, Western Blot
Size: 100ug
Form: Tris-citrate/phosphate buffer, pH 7 to 8
P type: Pab
Purity: Purified by immunoaffinity chromatography.
Additional info: This antibody is specific to the human ASPP1 protein. Species Crossreactivity: Human. Other species have not been tested.

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