ATF-1 Antibody

Cat no: 251171

Supplier: ABBIOTEC

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Description
Additional Information

Activating transcription factor 1 (ATF-1) is a protein that binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. ATF-1 binds to the Ta, Xenopus/Amphibian,-responsive element (TRE) of HTLV-I. ATF-1 mediates PKA-induced stimulation of CRE-reporter genes. Defects in ATF-1 are linked to angiomatoid fibrous histiocytoma (AFH). AFH is a distinct variant of malignant fibrous histiocytoma that typically occurs in children and adolescents and is manifest by nodular subcutaneous growth.

Catalogue number:	251171
Reactivities:	Human, Mouse, Chicken/Bird, Rabbit
Applications:	Immunohistochemistry
Size:	0.1 mg
Accession:	P18846
Antigen:	KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human ATF-1.
Format:	Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by immunogen affinity chromatography.
P type:	Rabbit Polyclonal Antibody
Isotype:	Rabbit Ig
Additional info:	ATF-1; Activating Transcription Factor-1; ATF1; Cyclic AMP-dependent transcription factor ATF-1; cAMP-dependent transcription factor ATF-1; Activating transcription factor 1; Protein TREB36