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Axonal Growth Cones

Axonal Growth Cones

Cat no: A4802-01C

Supplier: United States Biological
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This antibody recognizes an intracellular protein 2G13p which is restricted to growth cones in developing brain and embryonic neurons in culture. The protein 2G13p also appears to be associated with filamentous actin in the growth cones suggesting a role for 2G13p in growth cone motility.This antibody is suitable for use in immunohistological studies of both frozen and paraffin-embedded sections, staining growth cones, including their filopodia and lamellipodies. Applications: Suitable for use in Western Blot and Immunohistochemistry (Fr) (paraffin-embedded sections). Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: A4802-01C
Reactivities: Mouse, Rat, Chicken/Bird
Hosts: Mouse
Applications: Immunohistochemistry, Western Blot
Size: 1ml
Form: As reported
P type: Mab
Isotype: IgM
Purity: Tissue culture supernatant
References: Stettler O et al. Monoclonal antibody 2G13, a new axonal growth cone marker. J Neurocytol 28:1035-44 (1999).
Additional info: This antibody is useful as a general reagent for the detection of axonal growth cones in tissue sections and potentially a key marker in neuronal development research. Species Crossreactivity: Crossreacts with Rat, Mouse and Chicken.

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