B7-H4 Antibody

Cat no: 250473

Supplier: ABBIOTEC

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Description
Additional Information

Immune costimulatory protein B7-H4 (B7-H4) is e, Xenopus/Amphibian,pressed on the surface of a variety of immune cells and functions as a negative regulator of T cell response. By arresting cell cycle, B7-H4 inhibits growth, cytokine secretion and cytoto, Xenopus/Amphibian,icity development. When e, Xenopus/Amphibian,pressed on the cell surface of tumor macrophages, B7-H4 plays an important role, together with regulatory T-cells (Treg), in the suppression of tumor-associated antigen-specific T-cell immunity. B7-H4 is also involved in promoting epithelial cell transformation. B7-H4 can be a predictive marker for renal cell carcinoma.

Catalogue number:	250473
Reactivities:	Human, Mouse, Rabbit
Applications:	Immunohistochemistry
Size:	0.1 mg
Accession:	Q7Z7D3
Antigen:	KLH-conjugated synthetic peptide encompassing a sequence within the center region of human B7-H4.
Format:	Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
P type:	Rabbit Polyclonal Antibody
Isotype:	Rabbit Ig
Additional info:	V-set domain-containing T-cell activation inhibitor 1; Immune costimulatory protein B7-H4; B7h.5; T-cell costimulatory molecule B7, Xenopus/Amphibian,; Protein B7S1; VTCN1; B7H4